Quarterly Reviews of Biophysics covers the field of experimental and computational biophysics. Experimental biophysics span across different physics-based measurements such as optical microscopy, super-resolution imaging, electron microscopy, X-ray and neutron diffraction, spectroscopy, calorimetry, thermodynamics and their integrated uses. Computational biophysics includes theory, simulations, bioinformatics and system analysis. These biophysical methodologies are used to discover the structure, function and physiology of biological systems in varying complexities from cells, organelles, membranes, protein-nucleic acid complexes, molecular machines to molecules. The majority of reviews published are invited from authors who have made significant contributions to the field, who give critical, readable and sometimes controversial accounts of recent progress and problems in their specialty. The journal has long-standing, worldwide reputation, demonstrated by its high ranking in the ISI Science Citation Index, as a forum for general and specialized communication between biophysicists working in different areas. Thematic issues are occasionally published.

生物物理學(xué)的季度回顧涵蓋了實驗和計算生物物理學(xué)領(lǐng)域。實驗生物物理學(xué)跨越不同的物理基礎(chǔ)測量，如光學(xué)顯微鏡，超分辨率成像，電子顯微鏡，x射線和中子衍射，光譜學(xué)，量熱學(xué)，熱力學(xué)及其綜合應(yīng)用。計算生物物理學(xué)包括理論、模擬、生物信息學(xué)和系統(tǒng)分析。這些生物物理方法被用來發(fā)現(xiàn)從細(xì)胞、細(xì)胞器、膜、蛋白質(zhì)核酸復(fù)合物、分子機(jī)器到分子等各種復(fù)雜的生物系統(tǒng)的結(jié)構(gòu)、功能和生理。大多數(shù)發(fā)表的評論都是邀請對該領(lǐng)域做出重大貢獻(xiàn)的作者發(fā)表的，他們對自己專業(yè)領(lǐng)域的最新進(jìn)展和問題進(jìn)行了批判性的、可讀性強(qiáng)的、有時甚至是有爭議的描述。該雜志在ISI科學(xué)引文索引中排名靠前，是不同領(lǐng)域的生物物理學(xué)家之間進(jìn)行一般性和專業(yè)性交流的論壇，在世界范圍內(nèi)享有長期的聲譽(yù)。專題期刊偶爾出版。