The Journal of Physical Organic Chemistry is the foremost international journal devoted to the relationship between molecular structure and chemical reactivity in organic systems. It publishes Research Articles, Reviews and Mini Reviews based on research striving to understand the principles governing chemical structures in relation to activity and transformation with physical and mathematical rigor, using results derived from experimental and computational methods. Physical Organic Chemistry is a central and fundamental field with multiple applications in fields such as molecular recognition, supramolecular chemistry, catalysis, photochemistry, biological and material sciences, nanotechnology and surface science.

《物理有機化學雜志》是國際上最重要的關于有機體系中分子結構和化學反應性之間關系的雜志。它在研究的基礎上發表研究文章、評論和小評論，力求利用實驗和計算方法得出的結果，以物理和數學的嚴謹性理解與活動和轉化有關的化學結構的原理。物理有機化學是分子識別、超分子化學、催化、光化學、生物材料科學、納米技術和表面科學等領域的核心和基礎性領域。