Bioorganic & Medicinal Chemistry publishes complete accounts of research of outstanding significance and timeliness on all aspects of molecular interactions at the interface of chemistry and biology, together with critical review articles. The journal publishes reports of experimental results in medicinal chemistry, chemical biology and drug discovery and design, emphasizing new and emerging advances and concepts in these fields. The aim of the journal is to promote a better understanding at the molecular level of life processes, and living organisms, as well as the interaction of these with chemical agents.The Journal welcomes papers on:the medicinal chemistry and associated biology (including target identification and validation) of established or new disease targetsthe reporting of the discovery, design or optimization of potent new compounds or biological agentsthe analysis and discussion of structure-activity relationships and pharmacological issues relevant to drug design and action using in vitro and in vivo models, including the use of computational techniques when closely linked to experimental datathe reporting of "first-in-class" new therapeutic compoundsthe chemical biology or bioorganic/bioinorganic chemistry that significantly advances knowledge of a biological mechanismmethodological advances that are chemistry-based and which significantly impact on medicine or biologythe preparation and examination of biotherapeutics for the treatment of pathophysiological disease statesthe development of materials for specific therapeutic targetingAll manuscripts will be rigorously peer-reviewed by independent experts following an initial assessment by the Editors. Please note that BMC is not suitable for straightforward reports of incremental advances. Above all the presentation of a rational basis and a sound underlying hypothesis for the work is of particular importance, whatever its exact field.

《生物有機與藥物化學》發表了關于化學與生物學界面上分子相互作用各方面的顯著意義和及時性的完整研究報告，并發表了評論文章。該雜志發表了關于藥物化學、化學生物學和藥物發現與設計的實驗結果的報告，強調了這些領域新的和新出現的進展和概念。這本雜志的目的是促進人們更好地了解生命過程的分子水平、活生物體以及它們與化學試劑的相互作用。期刊歡迎發表以下論文：已建立或新的疾病靶點的藥物化學和相關生物學（包括靶點識別和確認）；發現、設計或優化有效新化合物或生物制劑的報告；利用體外和體內模型分析和討論與藥物設計和作用相關的結構-活性關系和藥理學問題，包括在與實驗數據密切相關時使用計算技術；“一流”新型治療化合物的報道；顯著提高生物機制知識的化學生物學或生物有機/生物無機化學；以化學為基礎，對醫學或生物學有重大影響的方法學進展；病理生理疾病狀態生物治療的制備與檢測；特定治療靶向材料的開發。所有手稿將由獨立專家在編輯初步評估后進行嚴格的同行評審。請注意，BMC不適合直接報告增量預付款。最重要的是，無論工作的確切領域是什么，合理的基礎和合理的基本假設的提出都是特別重要的。